Moving beyond conventional occlusion, Barrier Rescue provides immediate relief for extremely dry skin, with clinical proof of long-term barrier repair.

Worldwide, 1 September 2026

For decades, an impaired skin barrier has largely relied on petrochemical-based occlusives such as petrolatum, mineral oil, and paraffin. These ingredients temporarily reduce transepidermal water loss (TEWL) by forming a protective layer on the skin. While they provide immediate relief, they do not actively support the skin’s natural barrier repair processes, requiring regular reapplication to maintain their benefits.

As a pioneer in professional microbiome skincare, Esse believes barrier repair should go beyond occlusion. Barrier Rescue takes a biomimetic approach, combining skin-identical Ceramide NP and Castor Seed Oil with the world’s first COSMOS-certified, bio-based Propionic Acid, produced in partnership with a leading greentech company as a clean alternative to conventional petrochemical sources.

Propionic Acid supports microbiome balance, modulates inflammation, and strengthens barrier resilience.1–3 Together, these ingredients replenish the skin’s lipid matrix and help break the inflammation–dryness cycle.4–6

“Barrier dysfunction is rarely driven by a single factor,” says Kyle Groenewald, Head of R&D at Esse Skincare. “Long-term barrier repair requires supporting the microbiome, reducing inflammation, and replenishing skin-identical lipids, not simply relying on temporary occlusion.”

Barrier dysfunction is increasingly recognised as a contributing factor in persistent dryness, sensitivity, premature ageing, and impaired post-procedure recovery.7–9 In a four-week clinical study involving adults with dry and barrier-compromised skin, Barrier Rescue was clinically proven to improve skin barrier function, reducing transepidermal water loss (TEWL) by 10.7% after 28 days*.

Unlike conventional TEWL testing, which measures water loss while a product is still on the skin, Esse measured skin at least 8 hours after the last application. The results demonstrate that Barrier Rescue helps skin function better on its own between applications, rather than simply creating a temporary barrier to water loss.

Barrier Rescue is available through Esse’s global network of authorised professional partners.

* Based on studies conducted by an independent laboratory in Bonn, Germany.

About Esse Skincare
Founded by Trevor Steyn (MSc Chemistry), Esse Skincare is a professional microbiome skincare brand distributed in more than 42 countries. Through pioneering microbiome science and certified organic formulations, Esse develops products that work with the skin’s biology to support long-term skin health.

Media Enquiries: Amy Chu – Chief Marketing Officer
Esse Skincare: info@esseskincare.com | www.esseskincare.com

References

  1. Y. Wang, A. Dai, S. Huang, S. Kuo, M. Shu, C. P. Tapia, J. Yu, A. Two, H. Zhang, R. L. Gallo and C. M. Huang, Benef. Microbes, 2014, 5,
    161–168. doi:10.3920/BM2013.0031.
  2. X. Xiao, X. Hu, J. Yao, W. Cao, Z. Zou, L. Wang, H. Qin, D. Zhong, Y. Li, P. Xue, R. Jin, Y. Li, Y. Shi and J. Li, Front. Microbiol., 2023, 13,
    1–11. doi:10.3389/fmicb.2022.1083432.
  3. S. Almoughrabie, L. Cau, K. Cavagnero, A. M. O’Neill, F. Li, A. Roso-Mares, C. Mainzer, B. Closs, M. J. Kolar, K. J. Williams, S. J.
    Bensinger and R. L. Gallo, Sci. Adv., , DOI:10.1126/sciadv.adg6262. doi:10.1126/sciadv.adg6262.
  4. C. Vieira, S. Evangelista, R. Cirillo, A. Lippi, C. A. Maggi and S. Manzini, Mediators Inflamm., 2000, 9, 223–228.
    doi:10.1080/09629350020025737.
  5. M. M. Abomughaid, J. O. Teibo, O. A. Akinfe, A. M. Adewolu, T. K. A. Teibo, M. Afifi, A. M. H. Al-Farga, H. M. Al-kuraishy, A. I.
    Al-Gareeb, A. Alexiou, M. Papadakis and G. E. S. Batiha, Discover Applied Sciences, , DOI:10.1007/s42452-024-05964-5.
    doi:10.1007/s42452-024-05964-5.
  6. P. W. Wertz, M. C. Miethke, S. A. Long, J. S. Strauss and D. T. Downing, Journal of Investigative Dermatology, 1985, 84, 410–412.
    doi:10.1111/1523-1747.ep12265510.
  7. Z. Wang, M.-Q. Man, T. Li, P. M. Elias and T. M. Mauro, Aging, 2020, 12, 5551–5565. doi:10.18632/aging.102946.
  8. J. W. Fluhr, D. J. Moore, M. E. Lane, N. Lachmann and A. V. Rawlings, Journal of the European Academy of Dermatology and
    Venereology, 2024, 38, 812–820. doi:10.1111/jdv.19745.
  9. J. A. Segre, Journal of Clinical Investigation, 2006, 116, 1150–1158. doi:10.1172/JCI28521.

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